Manufacturing

Vanan is proud to be associated with a net work of well established reputed manufacturing firm to deliver Quality products. Adhering to high quality standards, the  state-of-the-art manufacturing facility focus on continuous improvement of technology & process, and conforms to international cGMP norms of WHO, qualified and dedicated human resources have been the cornerstones for building the company’s repute.

The plants are result of technology driven approach to serve the global emerging needs. The 3 facilities are dedicated to different dosage forms across the therapeutic segments. The infrastructure is equipped with sophisticated equipments and machines to meet the requirement of today and tomorrow.

Plant 1

• This facility is designed for manufacture of oral solids, and topical formulations.
• This integrated facility is located in Chennai, India. This plant conforms to WHO -GMP and GLP norms.

An overview of Topicals’ Manufacturing Facility

Topical plant has a built in area of 77500 square feet conforming to the global regulatory requirements with an Annual production capacity of 52.5 million Tubes.

• Dedicated manufacturing suites /product lines for steroid and non steroidal products manufacturing
• Provision for a total of 4 manufacturing suites two each for steroid and non steroid products
• In phase I, two Manufacturing suites commissioned, one dedicated suite each for Steroid and Non steroid products
• 500 kg Topical   Manufacturing Plant (Adam Fabriwek)
• Provision of SCADA  system
• Provision of dedicated CIP system for each manufacturing suite
• High Pressure Homogenizer
• 5 filling lines, 2 for steroids and 3 for Non steroid products
• In phase I, one tube Filling machine (Wimco-120 tube/min) along with cartoner and auto car toner (ACG) machines commissioned each for steroid & non steroid products
• Dedicated Purified Water system with distribution loop

Oral solids Capacity

Plant 2:

An  UK MHRA accredited facility dedicated to the oral solid dosage forms (Tablets and Capsules) with built in area of 40,000 sq.ft.

Manufacturing capacity:

• Tablets – 300 million / annum (On a single shift operation) Capsules (Hard Gelatin) – 160 million / annum (On a single shift operation)
• Rapid Mixer Granulator, Fluid Bed Processor & Fluid Bed Drier
• Auto coater (Sugar / Film & enteric coating) – 48” perforated pan
• Automatic blister packaging and cartonators unit with advanced rejection mechanisms
• CVC Bulk packing machine (60 bottles per minute)

The plant also conforms to US FDA; TGA which the company believes will be in line with its focus on exports in future and establishing its capabilities to supply products to the global market.

Plant 3:

This facility is located south of Chennai, India, dedicated to oral liquid formulations, with a built in area of 17,500 sq.meters containing four separate manufacturing, filling and packaging areas.

Production Capacity:

1. The manufacturing and packing operations are carried out in single shift. Two lines with single shift operation can deliver the following outputs.
   • 200 ml : 22.0 million bottles / annum (Line – I)
   • 100 ml / 60ml : 31.0 million bottles / annum (Line – II)
   • 15 ml     : 24.0 million bottles / annum (Line – II)
   • 100 ml / 60ml : 17.0 million bottles / annum (Line – III)
2. State-of-Art manufacturing facility with relevant automations
3. Dedicated Quality Control unit with separate space for Chemical Analysis, Instrumentation, Microbiological Analysis and Stability testing
4. Complete in-house utility systems, including DG Sets, Boiler, Compressed Air, Purified Water Systems and Dedicated HVAC System
5. Quality Management System is driven by QA with Documentation Cell as a part